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Index > Protein center > Manf(Gene name) > Rat
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  • Manf (Gene name),
  • Mesencephalic astrocyte-derived neurotrophic factor (Protein name ),  MANF_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Manf(Armet);
    Protein name:
    Mesencephalic astrocyte-derived neurotrophic factor;
    Alternative:
    Protein ARMET;Arginine-rich protein;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    179
    Sequence:
    50:
    MWATRGLAVA | LALSVLPDSR | ALRPGDCEVC | ISYLGRFYQD | LKDRDVTFSP | 
    100:
    ATIEEELIKF | CREARGKENR | LCYYIGATDD | AATKIINEVS | KPLAHHIPVE | 
    150:
    KICEKLKKKD | SQICELKYDK | QIDLSTVDLK | KLRVKELKKI | LDDWGEMCKG | 
    179:
    CAEKSDYIRK | INELMPKYAP | KAASARTDL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    E9615r
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    96T
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    ELISA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    E9615h
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    Packing:
    96T
    ELISA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    E9615m
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    ELISA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    E9615b
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    96T
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    CLIA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    U9615b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    U9615h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    U9615m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    U9615r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    P9615Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    P9615Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Cat.:
    P9615Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Monoclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Monoclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Monoclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Monoclonal Antibody for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Protein for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Protein for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Protein for Rat Mesencephalic astrocyte-derived neurotrophic factor
    Protein for Rat Mesencephalic astrocyte-derived neurotrophic factor

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    Precision
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    Linearity
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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons."
      Petrova P. , Raibekas A. , Pevsner J. , Vigo N. , Anafi M. , Moore M.K. , Peaire A.E. , Shridhar V. , Smith D.I. , Kelly J. , Durocher Y. , Commissiong J.W.
      J. Mol. Neurosci.20:173-188(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 45-54 AND 121-129;IDENTIFICATION BY MASS SPECTROMETRY
    3. 3.
      "Mesencephalic astrocyte-derived neurotrophic factor enhances nigral gamma-aminobutyric acid release."
      Zhou C. , Xiao C. , Commissiong J.W. , Krnjevic K. , Ye J.H.
      NeuroReport17:293-297(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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